University of Pittsburgh’s 125-node Apple Xserve G5 Cluster solves human genetics puzzles

“Every week in the CBS network’s new hit series Numb3rs, an FBI agent relies on his math genius brother to find patterns and equations that help to solve crimes. With its new Apple Xserve G5 computing cluster, the University of Pittsburgh’s Graduate School of Public Health (GSPH) is solving double-helix puzzles in human genetics every day — and faster than a speeding FBI-issue bullet,” The University of Pittsburgh Medical Center (UPMC) reports.

“Using the school’s newly installed 125-node Xserve cluster, more than 30 investigators and scientific teams, engaged in more than 120 complex research projects have all the computing power they could ask for, according to M. Michael Barmada, Ph.D., associate professor in the department of human genetics at GSPH. Paid for with a shared resource grant from the National Institutes of Health, the human genetics computing cluster is among the fastest at an academic medical center in the United States,” UPMC reports. “‘Our division of statistical genetics is looking for genes that influence diseases,’ explained Dr. Barmada, whose research focuses on the genetic epidemiology of common yet complex disorders such as diabetes and inflammatory bowel disease. ‘In a sense, we’re gene hunters.'”

UPMC reports, “Dr. Barmada and his colleagues are using their new computing power — dubbed locally as the Gattaca Cluster for the 1997 feature film — to analyze data involving the many genes that lead to variations in human traits, from those that regulate differences in height and bone density to those that influence susceptibility to disease. ‘With older computers, these complex calculations can take weeks,’ he said. ‘Insights into the factors that contribute to diseases give us targets for effective therapy. The new Gattaca Cluster is a terrific tool to help the discovery process.’ Future plans exist to extend Gattaca’s workload even more by analyzing data from microarrays and large SNP-chip studies, which can involve as many as 100,000 markers. ‘This will greatly increase the number of computations required for a genetics project, but Gattaca has the horsepower and storage capacity to handle whatever we throw at it,’ said Dr. Barmada.”

Full article here.

Related MacDailyNews articles:
Australia’s fastest supercomputer to use Apple Xserves, Xgrid and Mac OS X – April 20, 2005
Apple SoHo store to hold ‘Xserve G5 for High Performance Computing’ event on April 27 – April 09, 2005
Microsoft’s Windows Server for Supercomputers slips to ‘first half 2006’ – April 06, 2005
Apple announces high-performance computing U.S. tour – March 09, 2005
Louisville company partners with Apple to create ‘massively fast’ supercomputers for U.S. Navy – December 30, 2004
Virginia Tech’s ‘System X’ Apple Mac supercomputer places seventh in Top500 list – November 08, 2004
Virginia Tech ‘Big Mac’ System X achieves 12.25 teraflops – October 26, 2004
Virgina Tech’s faster ‘Big Mac’ System X supercomputer aims for top-ten world ranking – October 26, 2004
Father of Virginia Tech’s Power Mac G5 supercomputing cluster named among world’s top 100 scientists – September 21, 2004
U.S. Army’s 1,566 64-bit Apple Xserve G5 supercluster can exceed 25 teraflops – September 15, 2004
US Army’s ‘MACH 5’ Apple supercomputer opens eyes – July 05, 2004
US Army’s ‘MACH 5’ Apple supercomputer offers unmatched price/performance – June 24, 2004
COLSA to build ‘MACH 5’ Apple Xserve G5 supercomputer for US Army, to run Mac OS X ‘Panther’ Server – June 21, 2004
‘Big Mac’ Supercomputer may open enterprise market doors for Apple – February 12, 2004
Virginia Tech ‘Big Mac’ supercomputer attracting potential customers – January 28, 2004
Virginia Tech to upgrade ‘Big Mac’ supercomputer to Xserve G5 – January 27, 2004
Virginia Tech Power Mac G5 Supercomputer fires up today – September 24, 2003
Virginia Tech Power Mac G5 Supercomputer costs 90 percent less than nearest competitor – September 23, 2003
Virginia Tech Power Mac G5 supercomputer cluster to run on Mac OS X beta – September 03, 2003
Virginia Tech confirms use of 1,100 Power Mac G5’s for supercomputer cluster – September 02, 2003

15 Comments

  1. Way to go Apple! Now Apple helps with the study of human disease. Perfect.
    How many machines would it take with M$ OS to solve these problems?

    Millions, because they would become infected with virii faster than they could solve the problem!

Reader Feedback

This site uses Akismet to reduce spam. Learn how your comment data is processed.